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Office Hours:
On leave academic year 2007-08
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Jeremy Ward
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Assistant Professor of Biology
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McCardell Bicentennial Hall 353
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Phone: 802.443.3499
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Email: jward@middlebury.edu
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Degrees, Specializations & Interests:
Degrees:
Ph.D. Cornell University Medical College 2000 (Cancer Biology)
B.A. Cornell University 1994 (Cell Biology/Genetics)
Specialization: Mammalian Genetics
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Current Research:
My laboratory seeks to understand the gametogenic role of three mutations identified in this screen. In particular, we are interested in the biology of meiosis, chromosome dynamics and DNA damage repair. We use molecular genetics and functional genomics techniques to: genetically and physically map genes associated with gametogenesis, identify and clone candidate genes, and perform structure-function analysis of gametogenic genes.
Recent and Important Publications:
Ward JO, Reinholdt LG, Hartford SA, Wilson LA, Munroe RJ, Schimenti KJ, Libby BL, O'Brien M, Pendola JK, Eppig J and Schimenti JC. (2003). Toward the genetics of mammalian reproduction: Induction and mapping of gametogenesis mutants in mice. Biol Reprod. 69:1615–1625
Ward JO, McConnell M, Licht J, Freedman LP. (2001). The acute promyelocytic leukemia-associated protein, promyelocytic leukemia zinc finger, regulates 1,25-dihydroxyvitamin D3-induced monocytic differentiation of U937 cells through a physical interaction with vitamin D3 receptor. Blood. 98:3290-3300.
Rachez C, Suldan Z, Ward JO, Chang PB, Burakov D, Erdjument-Bromage H, Tempst P, Freedman LP. (1998). A novel protein complex that interacts with the vitamin D3 receptor in a ligand-dependent manner and enhances VDR transactivation in a cell free system. Genes Dev. 12:1787-1800.
Klemperer N, Ward JO, Evans E, Traktman P. (1997). The vaccinia virus I1 protein is essential for the assembly of mature virions. J Virol 71:9285-9294.
Recent Grants:
NIH R15, AREA. Identification and Characterization of the Mammalian Mutation Mei4. 9/06-8/09
VGN. Identification and Characterization of the Mammalian Mutation Mei4. 6/06-5/07
VGN. Identification of the Mammalian Meiotic Mutation Mei4. 9/05-5/06
NSF, MRI/RUI. Acquisition of DNA sequencing and Genotyping Instrumentation for Research and Undergraduate Training at Middlebury College. 8/03-6/0