Routes of drug administration in small mammals (Flecknell 1987) |
| |
Mouse |
Gerbil |
Hamster |
Rat |
Guinea pig |
Ferret |
Rabbit |
| Intramuscular |
Quadriceps 0.05 ml <23G |
Gluteal 0.05 ml <23G |
Gluteal 0.10ml <21G |
Quadriceps 0.30 ml <21G |
Quadriceps 0.30 ml <21G |
Quadriceps 0.50-1.00 ml<20G |
Quadriceps Lumbar muscles 0.05-1.00 ml <20G |
| Subcutaneous |
Scruff 2.00-3.00ml<20G |
Scruff 2.00-3.00 ml <20G |
Scruff 3.00-4.00 ml <20G |
Scruff 5.00-10.00ml<20G |
Scruff 5.00-10.00ml<20G |
Scruff 20.00-30.00ml<20G |
Scruff 30.00-50.00 ml<20G |
| Intraperitoneal |
Along line of hind limb 2.00-3.00 ml <21G |
10 degree angle to Abdominal wall 2.00-3.00 ml <21 G |
10 degree angle to Abdominal wall 3.00-4.00 ml <21G |
Along line to hind limb 5.00-10.00 ml <21G |
Along line to hind limb 10.00-15.00 ml <21 G |
Body cavity medial to hind limb 50.00-100.00 ml <20G |
90 degree paramedian mid abdomen 50.00- 100.00 ml <20G |
| Intravenous |
Lateral tail vein 0.20 ml <25G |
Lateral tail vein 0.20ml<25G |
Femoral or jugular vein (cut down) 0.30 ml<25G |
Lateral tail vein 0.50 ml <23G |
Ear vein Saphenous vein 0.50 ml <23G |
Cephalic vein 2.00-5.00ml (slowly)<21G |
Marginal ear vein 1.00-5.00 ml (slowly)<21G |
| Oral |
2OG catheter 0.25ml Bulb needle |
0.75 ml Bulb needle |
0.75 ml Bulb needle |
2OG catheter 1.0 ml Bulb needle |
1.0 ml Bulb needle |
Syringe in mouth 3.0 ml or stomach tube |
8G catheter 3.0 ml Syringe in mouth |
Maximum volumes are given for administration by the im, sc, ip and iv routes. Larger volumes than those indicated may be given by the oral route. However, those given are sufficient and safe for most purposes