Biology Seminar: Sourya Shertha, School of Public Health at Johns Hopkins

“Key drivers, and epidemiological dynamics of drug-resistant tuberculosis: A model-based approach”, talk by Dr. Sourya Shretha, School of Public Health at Johns Hopkins. For the first time in many decades, new first-line drug regimens are being considered for treatment of tuberculosis (TB), which is the leading infectious disease source of mortality in the world, with an estimated 1.8 million TB-related deaths in 2015. A key concern with the launch of new drug regimens is the potential for rapid emergence of resistance. Since population-level data on resistance cannot be collected in advance, epidemiological models become important tools for understanding the drivers and dynamics of resistance before novel drug regimens are launched. I will discuss model-based approach to uncover epidemiology of drug-resistant TB (DR-TB) by identifying roles of key drivers, and by describing short- and long-term dynamics of DR-TB.

Lunch will be available at 12:30pm.