McCardell Bicentennial Hall 216
276 Bicentennial Way
Middlebury, VT 05753
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Dr. Sarah Yip, Ph.D., MSc
Assistant Professor
Department of Psychiatry
Yale University School of Medicine

Can neuroimaging inform addiction treatment?
Despite advances, the effectiveness of most substance-use interventions remains highly variable across individuals and multiple quit-attempts are standard. This talk will present data indicating that neuroimaging may be used to identify individual difference factors contributing to variability in treatment responses, as well as brain-based targets for future intervention. This will include synthesis of prior work, as well as presentation of recent findings using connectome-based predictive modeling (CPM). CPM is a machine learning method of generating behavioral predictions from neuroimaging data (referred to as ‘neural fingerprinting’). Data demonstrating the ability of CPM to predict a real-world clinical outcome – abstinence from cocaine during 12-week treatment – will be presented and implications for future research will be discussed.

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